Complete genome sequences of Clostridium perfringens Del1 strain isolated from chickens affected by necrotic enteritis.

ABSTRACT:

Background

Clostridium perfringens is ubiquitous in nature. It is a normal inhabitant in the intestinal tract of animals and humans. As the primary etiological agent of gas gangrene, necrosis and bacteremia, C. perfringens causes food poisoning, necrotic enteritis (NE), and even death. Epidemiology research has indicated that the increasing incidence of NE in poultry is associated with the withdrawal of in-feed antibiotic growth promoters in poultry production in response to government regulations. The recent omics studies have indicated that bacterial virulence is typically linked to highly efficient conjugative transfer of toxins, or plasmids carrying antibiotic-resistance traits. Currently, there is limited information on understanding of host-pathogen interaction

SUBMITTER: Li C 

PROVIDER: S-EPMC5699181 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature