Effect of Intensive Blood Pressure Control on Gait Speed and Mobility Limitation in Adults 75 Years or Older: A Randomized Clinical Trial.

ABSTRACT:

Importance

Intensive blood pressure (BP) control confers a benefit on cardiovascular morbidity and mortality; whether it affects physical function outcomes is unknown.

Objective

To examine the effect of intensive BP control on changes in gait speed and mobility status.

Design, setting, and participants

This randomized, clinical trial included 2636 individuals 75 years or older with hypertension and no history of type 2 diabetes or stroke who participated in the Systolic Blood Pressure Intervention Trial (SPRINT). Data were collected from November 8, 2010, to December 1, 2015. Analysis was based on intention to treat.

Interventions

Participants were randomized to intensive treatment with a systolic BP target of less than 120 mm Hg (n = 1317) vs standard treatmen

SUBMITTER: Odden MC 

PROVIDER: S-EPMC5699455 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature