Measurements for 8 common analytes in native sera identify inadequate standardization among 6 routine laboratory assays.

ABSTRACT:

Background

External quality assessment (EQA) with commutable samples is essential for assessing the quality of assays performed by laboratories, particularly when the emphasis is on their standardization status and interchangeability of results.

Methods

We used a panel of 20 fresh-frozen single-donation serum samples to assess assays for the measurement of creatinine, glucose, phosphate, uric acid, total cholesterol, HDL cholesterol, LDL cholesterol, and triglycerides. The commercial random access platforms included: Abbott Architect, Beckman Coulter AU, Ortho Vitros, Roche Cobas, Siemens Advia, and Thermo Scientific Konelab. The assessment was done at the peer group level and by comparison against the all-method trimmed mean or reference method values, where available. The

SUBMITTER: Stepman HC 

PROVIDER: S-EPMC5699466 | biostudies-literature | 2014 Jun

REPOSITORIES: biostudies-literature