Chronic post-traumatic intramedullary lesions in dogs, a translational model.

ABSTRACT:

Objectives

Post-traumatic intramedullary myelopathies and cavitations are well described lesions following spinal cord injury (SCI) in humans and have been described in histopathological evaluations in dogs. Human intramedullary myelopathies/cavitations are associated with severe initial SCI and deterioration of clinical signs. Canine intervertebral disc extrusions share similarities with SCI in humans. In this descriptive study, magnetic resonance imaging (MRI) findings in spinal cords of dogs suffering from chronic post-traumatic myelopathies, including cavitations, are elucidated. An additional aim of the study was to compare diagnostic imaging and histopathological findings and identify similarities between human and canine chronic post-traumatic spinal cord lesions.

Methods

SUBMITTER: Alisauskaite N 

PROVIDER: S-EPMC5699804 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature