Associations between thyroid dysfunction and developmental status in children with excessive iodine status.

ABSTRACT: BACKGROUND AND OBJECTIVE:Adequate iodine status and normal thyroid hormone synthesis are important for optimal child development. In this study, we explored whether young children's developmental status is associated with thyroid dysfunction in an area of chronic excessive iodine exposure. METHODS:We included 298 children between 18 and 48 months of age residing in Algerian refugee camps. Early child development was measured using the Ages and Stages Questionnaires, third edition (ASQ-3), consisting of five domains: Communication, Gross Motor, Fine Motor, Problem Solving and Personal-Social. Due to poor discriminatory ability in the Gross Motor domain, the total ASQ-3 scores were calculated both including and excluding this domain. Urinary iodine concentration (UIC), thyroid hormones (TSH,

SUBMITTER: Aakre I 

PROVIDER: S-EPMC5699829 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature