Non-Surgical Therapy Reduces Presence of JP2 Clone in Localized Aggressive Periodontitis.

ABSTRACT:

Background

Previous studies have provided substantial evidence of the association of Aggregatibacter actinomycetemcomitans, and its highly leukotoxic JP2 genotype, with localized aggressive periodontitis (LAgP). The present study aims to evaluate presence of JP2 in individuals with LAgP after periodontal treatment.

Methods

Sixty African-American patients with LAgP, aged 5 to 25 years, were examined. At baseline, probing depth (PD), clinical attachment level (CAL), bleeding on probing, and plaque index were measured, and subgingival plaque was collected from LAgP diseased and healthy sites for each participant. Patients received whole-mouth ultrasonic debridement, scaling and root planing, and a 7-day prescription of amoxicillin and metronidazole. Participants were reevaluate

SUBMITTER: Burgess DK 

PROVIDER: S-EPMC5700858 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature