Linking Inter-Individual Variability in Functional Brain Connectivity to Cognitive Ability in Elderly Individuals.

ABSTRACT: Increasing evidence suggests that functional brain connectivity is an important determinant of cognitive aging. However, the fundamental concept of inter-individual variations in functional connectivity in older individuals is not yet completely understood. It is essential to evaluate the extent to which inter-individual variability in connectivity impacts cognitive performance at an older age. In the current study, we aimed to characterize individual variability of functional connectivity in the elderly and to examine its significance to individual cognition. We mapped inter-individual variability of functional connectivity by analyzing whole-brain functional connectivity magnetic resonance imaging data obtained from a large sample of cognitively normal older adults. Our results demonstra

SUBMITTER: Li R 

PROVIDER: S-EPMC5702299 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature