Application of non-Gaussian water diffusional kurtosis imaging in the assessment of uterine tumors: A preliminary study.

ABSTRACT:

Objectives

To evaluate the interobserver reliability and value of diffusional kurtosis imaging (DKI) in the assessment of uterine tumors compared with those of conventional diffusion-weighted imaging (DWI).

Methods

This retrospective study was approved by our institutional review board, which waived the requirement for informed consent. Fifty-eight women (mean age: 55.0 ± 13.6 years; range: 30-89 years) with suspected malignant uterine tumors underwent 3-T magnetic resonance imaging using DKI and DWI. Twelve had coexisting leiomyoma. Two observers analyzed region-of-interest measurements of diffusivity (D), kurtosis (K), and the apparent diffusion coefficient (ADC) of uterine lesions and healthy adjacent tissues. Interobserver agreement was evaluated using the intra-class co

SUBMITTER: Dia AA 

PROVIDER: S-EPMC5703480 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature