Long-term prognostic impact of left ventricular remodeling after a first myocardial infarction in modern clinical practice.

ABSTRACT:

Background

The association of left ventricular remodeling (LVR) after myocardial infarction (MI) with the subsequent risk of heart failure (HF) and death has not been studied in patients receiving optimal secondary prevention.

Methods and results

We performed a long-term clinical follow-up of patients included in 2 prospective multicentric studies on LVR after first anterior MI. At 1-year echocardiography, LVR (≥20% increase in end-diastolic volume from baseline to 1 year) occurred in 67/215 (31%) patients in cohort 1 and in 87/226 (38%) patients in cohort 2. The prescription rate of secondary prevention medications was very high (ß-blockers at 1 year: 90% and 95% for cohorts 1 and 2, respectively; angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers

SUBMITTER: Bauters C 

PROVIDER: S-EPMC5703528 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature