Quantifying bone marrow inflammatory edema in the spine and sacroiliac joints with thresholding.

ABSTRACT:

Background

Psoriatic Arthritis (PsA) is a chronic inflammatory arthritis that develops in patients with psoriasis. Inflammatory edema in the spine may reflect subclinical disease activity and be a predictor of radiographic progression. A semi-quantitative method established by the spondyloarthritis research consortium of Canada (SPARCC) is commonly used to assess the disease activity in MR images of the spine. This study aims to evaluate thresholding for quantification of subtle bone marrow inflammation in the spine and the sacroiliac (SI) joints of patients with PsA and compare it with the SPARCC scoring system.

Methods

Short tau inversion recovery (STIR) MR images of the spine (N = 85) and the SI joints (N = 95) of patients with PsA (N = 41) were analyzed. A threshold was

SUBMITTER: Chronaiou I 

PROVIDER: S-EPMC5704357 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature