The incidence of congenital hypothyroidism (CH) in Guangxi, China and the predictors of permanent and transient CH.

ABSTRACT: BACKGROUND:The incidence of congenital hypothyroidism (CH) differs significantly among different ethnicities and regions, and early differentiation of transient CH is important to avoid unnecessary prolonged treatment with L-T4. OBJECTIVE:To investigate the incidence of CH based on the newborn screening program in Guangxi Zhuang Autonomous Region, China, and to analyze the predictors that might allow for an early differentiation between permanent (P) and transient (T) CH. DESIGN AND METHODS:Data from newborn screening program over a seven-year period (January 2009 to January 2016) at Guangxi Maternal and Child Health Hospital are analyzed. Blood samples were collected on filter paper between 3 and 7 days after birth, and TSH level was measured by time-resolved fluorescence assay. Individua

SUBMITTER: Fu C 

PROVIDER: S-EPMC5704446 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature