Cytotoxic activity of NN-32 toxin from Indian spectacled cobra venom on human breast cancer cell lines.

ABSTRACT:

Background

Breast cancer is the most common cancer which causes significant morbidity and mortality among women worldwide. Lack of medical facilities for early detection, therapeutic strategies for treatment and side effects due to pharmacological compounds have encompassed the need for new therapies mostly from natural sources. A lot of components have been identified from different snake venoms as therapeutic agents. A group of polypeptides (60-70 amino acid residues) called cytotoxins or cardiotoxins present in an elapid family of snakes have a wide variety of pharmaceutical actions and have the tendency to damage a wide variety of cells including cancerous cells. The aim of the present study was to evaluate the cytotoxic effect of NN-32 protein toxin purified from Indian Specta

SUBMITTER: Attarde SS 

PROVIDER: S-EPMC5704554 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature