Shift work, night work, and the risk of prostate cancer: A meta-analysis based on 9 cohort studies.

ABSTRACT:

Background

Epidemiology studies suggested that shift work or night work may be linked to prostate cancer (PCa); the relationship, however, remains controversy.

Methods

PubMed, ScienceDirect, and Embase (Ovid) databases were searched before (started from the building of the databases) February 4, 2017 for eligible cohort studies. We pooled the evidence included by a random- or fixed-effect model, according to the heterogeneity. A predefined subgroup analysis was conducted to see the potential discrepancy between groups. Sensitivity analysis was used to test whether our results were stale.

Results

Nine cohort studies were eligible for meta-analysis with 2,570,790 male subjects. Our meta-analysis showed that, under the fixed-effect model, the pooled relevant risk (RR) of

SUBMITTER: Du HB 

PROVIDER: S-EPMC5704803 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature