Ontology highlight
ABSTRACT:
SUBMITTER: Levin BJ
PROVIDER: S-EPMC5705181 | biostudies-literature | 2017 Feb
REPOSITORIES: biostudies-literature
Levin B J BJ Huang Y Y YY Peck S C SC Wei Y Y Martínez-Del Campo A A Marks J A JA Franzosa E A EA Huttenhower C C Balskus E P EP
Science (New York, N.Y.) 20170201 6325
The human microbiome encodes vast numbers of uncharacterized enzymes, limiting our functional understanding of this community and its effects on host health and disease. By incorporating information about enzymatic chemistry into quantitative metagenomics, we determined the abundance and distribution of individual members of the glycyl radical enzyme superfamily among the microbiomes of healthy humans. We identified many uncharacterized family members, including a universally distributed enzyme ...[more]