New insights from a high-resolution look at gastrulation in the sea urchin, Lytechinus variegatus.

ABSTRACT:

Background

Gastrulation is a complex orchestration of movements by cells that are specified early in development. Until now, classical convergent extension was considered to be the main contributor to sea urchin archenteron extension, and the relative contributions of cell divisions were unknown. Active migration of cells along the axis of extension was also not considered as a major factor in invagination.

Results

Cell transplantations plus live imaging were used to examine endoderm cell morphogenesis during gastrulation at high-resolution in the optically clear sea urchin embryo. The invagination sequence was imaged throughout gastrulation. One of the eight macromeres was replaced by a fluorescently labeled macromere at the 32 cell stage. At gastrulation those patches of f

SUBMITTER: Martik ML 

PROVIDER: S-EPMC5705275 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature