Human parainfluenza virus infection in severe acute respiratory infection cases in Beijing, 2014-2016: A molecular epidemiological study.

ABSTRACT:

Background

Severe acute respiratory infection (SARI) threatens human health and even survival, causing a huge number of hospitalized patients every year. However, as one of the most common respiratory viruses circulated worldwide, the epidemiological and phylogenetic characteristics of human parainfluenza virus (HPIV) in these cases were not well known.

Objectives

To reveal the epidemiological features of HPIV infection in SARIs in Beijing area from September 2014 to August 2016.

Methods

A total of 1229 SARI cases in Beijing area were enrolled, investigated, sampled, and tested by multiplex real-time PCR to identify HPIVs and other common respiratory viruses. Eighteen HPIV-3 viruses isolated from all HPIV-positive samples in these SARI cases were sequenced and analyze

SUBMITTER: Pan Y 

PROVIDER: S-EPMC5705688 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature