Thyroid Hormone Stimulates the Onset of Adult Feeding Kinematics in Zebrafish.

ABSTRACT: The physical demands for swimming and feeding change dramatically over the course of development for many aquatic animals. Indeed, in teleosts, the transition from larva to adult involves major shifts in both trophic morphology and feeding behavior. A spike in thyroid hormone (TH) coordinates many developmental processes that occur during this adult transition in numerous vertebrate species. Using mutant and transgenic zebrafish, we tested the hypothesis that TH is essential for the transition from larval to adult feeding kinematic profiles. We found that every measured kinematic variable that distinguished larvae from adults also differentiated hypothyroid from wild-type (WT) euthyroid adults, suggesting that TH is indeed necessary for the onset of mature feeding behaviors. In contrast, f

SUBMITTER: McMenamin S 

PROVIDER: S-EPMC5706621 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature