Prognostic markers for survival in patients with oligodendroglial tumors; a single-institution review of 214 cases.

ABSTRACT:

Background

In the 2016 WHO classification, the diagnosis of oligodendroglioma has been restricted to IDH mutated, 1p19q codeleted tumors (IDHmut-codel). IDHmut oligoastrocytoma is now classified either as oligodendroglioma or astrocytoma based on presence of 1p19q codeletion. There is growing evidence that this molecular classification more closely reflects patient outcome. Due to the strong association between IDHmut-codel with oligodendroglial morphology, the additional impact of these markers on prognostic accuracy is largely unknown. Our aim was to assess the prognostic impact of IDHmut-codel in an unselected cohort of morphologically classified oligodendroglial tumors.

Methods

We performed a retrospective chart review of oligodendroglial tumors (WHO grade II and III) op

SUBMITTER: Zetterling M 

PROVIDER: S-EPMC5706698 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature