Prognostic group stratification and nomogram for predicting overall survival in patients who received radiotherapy for abdominal lymph node metastasis from hepatocellular carcinoma: a multi-institutional retrospective study (KROG 15-02).

ABSTRACT:

Objective

To develop a prognostic model for overall survival (OS) in hepatocellular carcinoma (HCC) patients receiving radiotherapy (RT) to metastatic abdominal lymph nodes (LNs).

Materials and methods

Two hundred twenty-eight patients treated with RT to metastatic abdominal LNs were retrospectively reviewed.

Results

Median OS in all patients was 11.1 months. LN responders had significantly higher median OS than non-responders (14.2 months vs. 7.5 months, p<0.05). On multivariate analysis, Child-Pugh classification, status of intrahepatic tumor, presence of distant metastasis, number and location of metastatic LNs, serum level of alpha fetoprotein (AFP), and the LN response to RT were significant prognostic factors for OS (p < 0.05 each). Based on the re

SUBMITTER: Kim Y 

PROVIDER: S-EPMC5706887 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature