Using iterative learning to improve understanding during the informed consent process in a South African psychiatric genomics study.

ABSTRACT: Obtaining informed consent is a great challenge in global health research. There is a need for tools that can screen for and improve potential research participants' understanding of the research study at the time of recruitment. Limited empirical research has been conducted in low and middle income countries, evaluating informed consent processes in genomics research. We sought to investigate the quality of informed consent obtained in a South African psychiatric genomics study. A Xhosa language version of the University of California, San Diego Brief Assessment of Capacity to Consent Questionnaire (UBACC) was used to screen for capacity to consent and improve understanding through iterative learning in a sample of 528 Xhosa people with schizophrenia and 528 controls. We address two quest

SUBMITTER: Campbell MM 

PROVIDER: S-EPMC5707000 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature