Outcomes and patterns of care in a nationwide cohort of pediatric medulloblastoma: Factors affecting proton therapy utilization.

ABSTRACT:

Purpose

We examined national outcomes and patterns of care for pediatric patients with medulloblastoma (MB) in a large observational cohort.

Methods and materials

Using the National Cancer Database, we evaluated the clinical features and survival outcomes of patients diagnosed with MB. The association between intervention, covariables, and outcome was assessed in a multivariable Cox analysis and through logistic regression analysis. Survival was estimated using the Kaplan-Meier method.

Results

Among the 4032 patients in the National Cancer Database with pediatric brain tumors, 1300 patients met the inclusion criteria of histologic diagnosis, receipt of chemotherapy and radiation, and age ≤18 years. The median age and follow-up were 8.4 years and 4.5 years, respectivel

SUBMITTER: Kopecky AS 

PROVIDER: S-EPMC5707421 | biostudies-literature | 2017 Oct-Dec

REPOSITORIES: biostudies-literature