Characterizing the role of the hippocampus during episodic simulation and encoding.

ABSTRACT: The hippocampus has been consistently associated with episodic simulation (i.e., the mental construction of a possible future episode). In a recent study, we identified an anterior-posterior temporal dissociation within the hippocampus during simulation. Specifically, transient simulation-related activity occurred in relatively posterior portions of the hippocampus and sustained activity occurred in anterior portions. In line with previous theoretical proposals of hippocampal function during simulation, the posterior hippocampal activity was interpreted as reflecting a transient retrieval process for the episodic details necessary to construct an episode. In contrast, the sustained anterior hippocampal activity was interpreted as reflecting the continual recruitment of encoding and/or rela

SUBMITTER: Thakral PP 

PROVIDER: S-EPMC5708138 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature