Door-to-Needle Delays in Minor Stroke: A Causal Inference Approach.

ABSTRACT:

Background and purpose

Thrombolysis rates among minor stroke (MS) patients are increasing because of increased recognition of disability in this group and guideline changes regarding treatment indications. We examined the association of delays in door-to-needle (DTN) time with stroke severity.

Methods

We performed a retrospective analysis of all stroke patients who received intravenous tissue-type plasminogen activator in our emergency department between July 1, 2011, and February 29, 2016. Baseline characteristics and DTN were compared between MS (National Institutes of Health Stroke Scale score ≤5) and nonminor strokes (National Institutes of Health Stroke Scale score >5). We applied causal inference methodology to estimate the magnitude and mechanisms of the causal effect

SUBMITTER: Rostanski SK 

PROVIDER: S-EPMC5708142 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature