Comprehensive analysis of early fractional anisotropy changes in acute ischemic stroke.

ABSTRACT:

Background and purpose

Cerebral ischemia leads to a rapid decrease of the apparent diffusion coefficient. For fractional anisotropy both increase and decrease have been reported in acute ischemic stroke. Aim of this study was to characterize early water diffusion changes in a homogenous group of acute stroke patients and to clarify the issue of early fractional anisotropy changes and their relation to time from symptom onset.

Methods

MRI data of patients with acute ischemic stroke examined by diffusion tensor imaging within 8h after symptom were analyzed. We calculated fractional anisotropy, eigenvalues and the isotropic and anisotropic components of the diffusion tensor. The values were calculated as ratios between the ischemic lesion and a mirror region in the unaffected s

SUBMITTER: Alegiani AC 

PROVIDER: S-EPMC5708650 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature