The role of a palliative care intervention in moderating the relationship between depression and survival among individuals with advanced cancer.

ABSTRACT:

Objective

Randomized controlled trials (RCTs) of early palliative care interventions in advanced cancer have positively impacted patient survival, yet the mechanisms remain unknown. This secondary analysis of 2 RCTs assessed whether an early palliative care intervention moderates the relationship between depressive symptoms and survival.

Method

The relationships among mood, survival, and early palliative care intervention were studied among 529 advanced cancer patients who participated in 2 RCTs. The first (N = 322) compared intervention versus usual care. The second (N = 207) compared early versus delayed intervention (12 weeks after enrollment). The interventions included an in-person consultation, weekly nurse coach-facilitated phone sessions, and monthly follow-up. Mood

SUBMITTER: Prescott AT 

PROVIDER: S-EPMC5709150 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature