Effect of androgen deprivation therapy on sexual function and bother in men with prostate cancer: A controlled comparison.

ABSTRACT:

Objectives

The adverse sexual effects of androgen deprivation therapy (ADT) on men with prostate cancer have been well described. Less well known is the relative degree of sexual dysfunction and bother associated with ADT compared to other primary treatment modalities such as radical prostatectomy. We sought to describe the trajectory and relative magnitude of changes in sexual function and bother in men on ADT and to examine demographic and clinical predictors of ADT's adverse sexual effects.

Methods

Prostate cancer patients treated with ADT (n = 60) completed assessments of sexual function and sexual bother 3 times during a 1-year period after the initiation of ADT. Prostate cancer patients treated with radical prostatectomy only and not receiving ADT (n = 85) and men with

SUBMITTER: Donovan KA 

PROVIDER: S-EPMC5709275 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature