Relationship of changes in strain rate indices estimated from velocity-encoded MR imaging to loss of muscle force following disuse atrophy.

ABSTRACT:

Purpose

This study explores changes in strain rate (SR) (rate of regional deformation) parameters extracted from velocity-encoded MRI and their relationship to muscle force loss following 4-week unilateral lower limb suspension in healthy humans.

Methods

Two-dimensional SR maps were derived from three directional velocity-encoded MR phase-contrast images of the medial gastrocnemius in seven subjects. Atrophy-related and regional differences in the SR eigenvalues, angle between the SR and muscle fiber (SR-fiber angle), and strain rates in the fiber basis were statistically analyzed using analysis of variance and linear regression.

Results

During isometric contraction, SR in the fiber cross section (SR_in-plane ) was significantly lower, and the SR-fiber angle

SUBMITTER: Malis V 

PROVIDER: S-EPMC5709278 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature