In vivo selection of a multidrug-resistant Aeromonas salmonicida during medicinal leech therapy.

ABSTRACT: We report the selection in a 15-year-old boy of a multidrug-resistant, extended-spectrum β-lactamase (ESBL)-producing Aeromonas salmonicida after medicinal leech therapy that required an antibiotic prophylaxis based on piperacillin/tazobactam and cotrimoxazole. Whole genome sequencing of the strain indeed revealed 13 antibiotic resistance genes, including the ESBL CTX-M-3 and the unusual β-lactamase SCO-1.

SUBMITTER: Ruppe E 

PROVIDER: S-EPMC5709350 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature