Brief training in mindfulness may normalize a blunted error-related negativity in chronically depressed patients.

ABSTRACT: The error-related negativity (ERN), an evoked-potential that arises in response to the commission of errors, is an important early indicator of self-regulatory capacities. In this study we investigated whether brief mindfulness training can reverse ERN deficits in chronically depressed patients. The ERN was assessed in a sustained attention task. Chronically depressed patients (n = 59) showed significantly blunted expression of the ERN in frontocentral and frontal regions, relative to healthy controls (n = 18). Following two weeks of training, the patients (n = 24) in the mindfulness condition showed a significantly increased ERN magnitude in the frontal region, but there were no significant changes in patients who had received a resting control (n = 22). The findings suggest that brief tr

SUBMITTER: Fissler M 

PROVIDER: S-EPMC5709439 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature