Risk stratification models for para-aortic lymph node metastasis and recurrence in stage IB-IIB cervical cancer.

ABSTRACT:

Objective

To examine the surgical-pathological predictors of para-aortic lymph node (PAN) metastasis at radical hysterectomy, and for PAN recurrence among women who did not undergo PAN dissection at radical hysterectomy.

Methods

This is a retrospective analysis of a nation-wide cohort study of surgically-treated stage IB-IIB cervical cancer (n=5,620). Multivariate models were used to identify independent surgical-pathological predictors for PAN metastasis/recurrence.

Results

There were 120 (2.1%) cases of PAN metastasis at surgery with parametrial involvement (adjusted odds ratio [aOR]=1.65), deep stromal invasion (aOR=2.61), ovarian metastasis (aOR=3.10), and pelvic nodal metastasis (single-node aOR=5.39 and multiple-node aOR=33.5, respectively) being independent ris

SUBMITTER: Matsuo K 

PROVIDER: S-EPMC5709521 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature