Assessing loss to follow-up in the MObile Technology for Improved Family Planning (MOTIF) randomised controlled trial.

ABSTRACT:

Background

Loss to follow-up (LTFU) in clinical trials is an important source of bias that can affect statistical power and generalisability of findings. The aim of this paper is to assess factors associated with LTFU in the MObile Technology for Improved Family Planning (MOTIF) trial in Cambodia and compare how the result might have varied using different analytical methods.

Methods

Follow-up in the MOTIF trial was 86% at 4 months and 66% at 12 months. For the primary analysis, we undertook a complete case analysis, similar to the approach used in similar trials of interventions delivered by mobile phone to increase contraception use. We conducted an exploratory analysis and found that factors associated with LTFU were young age, lower socio-economic status, not planning to

SUBMITTER: Smith C 

PROVIDER: S-EPMC5709838 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature