COMT genotype and non-recovery after a whiplash injury in a Northern European population.

ABSTRACT:

Background

The COMT (Catechol-O-Methyl Transferase) gene may influence a person's vulnerability to develop long-term pain and some COMT single nucleotide polymorphisms (SNPs) may associate with patterns of acute or chronic pain. Many patients with whiplash-associated disorders (WADs) suffer from long-term pain and other related symptoms, but it is less known if genetic factors play a role in the recovery process. The primary aim of this study was to evaluate whether self-reported non-recovery, including pain, was related to COMT genotype in patients with WAD. The secondary aim was to investigate whether or not background factors, including mental health, were related to genotype and non-recovery.

Methods

A total of 133 patients with neck pain after a whiplash trauma were inc

SUBMITTER: Rydman E 

PROVIDER: S-EPMC5709856 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature