"Does the Salmonella Genomic Island 1 (SGI1) confer invasiveness properties to human isolates?"

ABSTRACT:

Background

In the eighties, a multidrug resistant clone of Salmonella Typhimurium DT104 emerged in UK and disseminated worldwide. This clone harbored a Salmonella genomic island 1 (SGI1) that consists of a backbone and a multidrug resistant region encoding for penta-resistance (ampicillin, chloramphenicol/florfenicol, streptomycin/spectinomycin, sulphonamides and tetracycline (ACSSuT)). Several authors suggested that SGI1 might have a potential role in enhancement of virulence properties of Salmonella enterica. The aim of this study was to investigate whether nontyphoidal S. enterica isolates carrying SGI1 cause more severe illness than SGI1 free ones in humans.

Methods

From 2011 to 2016, all patients infected with nontyphoidal S. enterica in our hospital were retrospectivel

SUBMITTER: de Curraize C 

PROVIDER: S-EPMC5709944 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature