Effects of Oral vs Transdermal Estrogen Therapy on Sexual Function in Early Postmenopause: Ancillary Study of the Kronos Early Estrogen Prevention Study (KEEPS).

ABSTRACT:

Importance

Sexual dysfunction, an important determinant of women's health and quality of life, is commonly associated with declining estrogen levels around the menopausal transition.

Objective

To determine the effects of oral or transdermal estrogen therapy vs placebo on sexual function in postmenopausal women.

Design, setting, and participants

Ancillary study of the Kronos Early Estrogen Prevention Study (KEEPS), a 4-year prospective, randomized, double-blinded, placebo-controlled trial of menopausal hormone therapy in healthy, recently menopausal women. Of 727 KEEPS enrollees, 670 agreed to participate in this multicenter ancillary study. Women were 42 to 58 years old, within 36 months from last menstrual period. Data were collected from July 2005 through June 2008

SUBMITTER: Taylor HS 

PROVIDER: S-EPMC5710212 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature