Natural History and Tumor Volume Kinetics of Papillary Thyroid Cancers During Active Surveillance.

ABSTRACT:

Importance

Active surveillance of low-risk papillary thyroid cancer (PTC) is now an accepted alternative to immediate surgery, but experience with this approach outside of Japan is limited. The kinetics (probability, rate, and magnitude) of PTC tumor growth under active surveillance have not been well defined.

Objective

To describe the kinetics of PTC tumor growth during active surveillance.

Design, setting, and participants

Cohort study of 291 patients undergoing active surveillance for low-risk PTC (intrathyroidal tumors ≤1.5 cm) with serial tumor measurements via ultrasonography at a tertiary referral center in the United States.

Intervention

Active surveillance.

Main outcomes and measures

The cumulative incidence, rate, and magnitude of the change in

SUBMITTER: Tuttle RM 

PROVIDER: S-EPMC5710258 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature