Association of Thyroid Function With Life Expectancy With and Without Cardiovascular Disease: The Rotterdam Study.

ABSTRACT:

Importance

Variations in thyroid function within reference ranges are associated with an increased risk of cardiovascular disease (CVD) and mortality. However, the impact of thyroid function on life expectancy (LE) and the number of years lived with and without CVD remains unknown.

Objective

To investigate the association of thyroid function with total LE and LE with and without CVD among euthyroid individuals.

Design, setting, and participants

The Rotterdam Study, a population-based, prospective cohort study. We included participants without known thyroid disease and with thyrotropin and free thyroxine (FT4) levels within the reference ranges.

Main outcomes and measures

Multistate life tables were used to calculate total LE and LE with and without CVD among th

SUBMITTER: Bano A 

PROVIDER: S-EPMC5710266 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature