Age-Related Macular Degeneration in Patients With Chronic Myeloproliferative Neoplasms.

ABSTRACT:

Importance

It has been suggested that systemic inflammation increases the risk of age-related macular degeneration (AMD). Given that chronic immune modulation is present in patients with myeloproliferative neoplasms (MPNs), the risk of AMD in these patients may be increased.

Objective

To compare the risk of AMD in patients with MPNs with the risk of AMD in matched controls from the general population.

Design, setting, and participants

A nationwide population-based cohort study using Danish registers was conducted of all patients in Denmark who received a diagnosis between January 1, 1994, and December 31, 2013, of essential thrombocythemia, polycythemia vera, myelofibrosis, or unclassifiable MPNs. For each patient, 10 age- and sex-matched controls were included. All p

SUBMITTER: Bak M 

PROVIDER: S-EPMC5710292 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature