Risk of Intraocular Bleeding With Novel Oral Anticoagulants Compared With Warfarin: A Systematic Review and Meta-analysis.

ABSTRACT:

Importance

It is unclear if the risk of intraocular bleeding with novel oral anticoagulants differs compared with warfarin.

Objective

To characterize the risk of intraocular bleeding with novel oral anticoagulants compared with warfarin.

Data sources

A systematic review and meta-analysis was undertaken in an academic medical setting. MEDLINE and ClinicalTrials.gov were searched for randomized clinical trials published up until August 2016. This search was supplemented by manual bibliography searches of identified trials and other review articles.

Study selection

Studies were eligible for inclusion if they were phase 3 randomized clinical trials, enrolled patients with atrial fibrillation or venous thromboembolism, compared a novel oral anticoagulant (dabigatran

SUBMITTER: Sun MT 

PROVIDER: S-EPMC5710315 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature