Association Between Pregnancy and Perinatal Outcomes Among Women With Epilepsy.

ABSTRACT:

Importance

To date, few attempts have been made to examine associations between exposure to maternal epilepsy with or without antiepileptic drug (AED) therapy and pregnancy and perinatal outcomes.

Objectives

To investigate associations between epilepsy in pregnancy and risks of pregnancy and perinatal outcomes as well as whether use of AEDs influenced risks.

Design, setting, and participants

A population-based cohort study was conducted on all singleton births at 22 or more completed gestational weeks in Sweden from 1997 through 2011; of these, 1 424 279 were included in the sample. Information on AED exposure was available in the subset of offspring from July 1, 2005, to December 31, 2011. Data analysis was performed from October 1, 2016, to February 15, 2017.

Mai

SUBMITTER: Razaz N 

PROVIDER: S-EPMC5710333 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature