Association of Short Antenatal Corticosteroid Administration-to-Birth Intervals With Survival and Morbidity Among Very Preterm Infants: Results From the EPICE Cohort.

ABSTRACT:

Importance

Administration-to-birth intervals of antenatal corticosteroids (ANS) vary. The significance of this variation is unclear. Specifically, to our knowledge, the shortest effective administration-to-birth interval is unknown.

Objective

To explore the associations between ANS administration-to-birth interval and survival and morbidity among very preterm infants.

Design, setting, and participants

The Effective Perinatal Intensive Care in Europe (EPICE) study, a population-based prospective cohort study, gathered data from 19 regions in 11 European countries in 2011 and 2012 on 4594 singleton infants with gestational ages between 24 and 31 weeks, without severe anomalies and unexposed to repeated courses of ANS. Data were analyzed November 2016.

Exposure

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SUBMITTER: Norman M 

PROVIDER: S-EPMC5710338 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature