Diagnostic Accuracy of Fecal Immunochemical Test in Patients at Increased Risk for Colorectal Cancer: A Meta-analysis.

ABSTRACT:

Importance

The potential role of the fecal immunochemical test (FIT) for screening patients at increased risk for colorectal cancer (CRC) has not yet been elucidated.

Objective

To assess the diagnostic accuracy of FIT for CRC or advanced neoplasia (AN) in asymptomatic patients at above-average risk.

Data sources

MEDLINE, EMBASE, Cochrane Library, and gray literature sources through August 2016.

Study selection

Diagnostic studies evaluating the accuracy of FIT for CRC or AN in patients with a personal or familial history of CRC using colonoscopy as the reference standard.

Data extraction and synthesis

Two authors (A.K. and P.P.) independently extracted data and evaluated study quality using the Quality Assessment of Diagnostic Accuracy Studies-2 tool, and

SUBMITTER: Katsoula A 

PROVIDER: S-EPMC5710432 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature