Safety of Systemic Agents for the Treatment of Pediatric Psoriasis.

ABSTRACT:

Importance

Use of systemic therapies for moderate to severe psoriasis in children is increasing, but comparative data on their use and toxicities are limited.

Objective

To assess patterns of use and relative risks of systemic agents for moderate to severe psoriasis in children.

Design, setting, and participants

A retrospective review was conducted at 20 centers in North America and Europe, and included all consecutive children with moderate to severe psoriasis who used systemic medications or phototherapy for at least 3 months from December 1, 1990, to September 16, 2014.

Main outcomes and measures

The minimal core data set included age, sex, severity of psoriasis, systemic interventions, monitoring, adverse events (AEs), and reason for discontinuation.

Resu

SUBMITTER: Bronckers IMGJ 

PROVIDER: S-EPMC5710436 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature