Percutaneous Coronary Intervention vs Coronary Artery Bypass Grafting in Patients With Left Main Coronary Artery Stenosis: A Systematic Review and Meta-analysis.

ABSTRACT:

Importance

In patients with left main coronary artery (LMCA) stenosis, coronary artery bypass grafting (CABG) has been the standard therapy for several decades. However, some studies suggest that percutaneous coronary intervention (PCI) with drug-eluting stents may be an acceptable alternative.

Objective

To compare the long-term safety of PCI with drug-eluting stent vs CABG in patients with LMCA stenosis.

Data sources

PubMed, Scopus, EMBASE, Web of Knowledge, and ScienceDirect databases were searched from December 18, 2001, to February 1, 2017. Inclusion criteria were randomized clinical trial, patients with LMCA stenosis, PCI vs CABG, exclusive use of drug-eluting stents, and clinical follow-up of 3 or more years.

Data extraction and synthesis

Trial-level haza

SUBMITTER: Giacoppo D 

PROVIDER: S-EPMC5710445 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature