Outcomes in Women With Cytology Showing Atypical Squamous Cells of Undetermined Significance With vs Without Human Papillomavirus Testing.

ABSTRACT:

Importance

Little is known about the long-term yield of high-grade cervical intraepithelial neoplasia (CIN) and the influence on biopsy and treatment rates of human papillomavirus (HPV) triage of cytology showing atypical squamous cells of undetermined significance (hereafter ASC-US cytology).

Objective

To examine 5-year outcomes after ASC-US cytology with vs without HPV testing.

Design, setting, and participants

In this observational study, all cervical cytology and HPV testing reports from January 1, 2007, to December 31, 2012, were obtained for women throughout New Mexico and linked to pathology reports. The dates of the analysis were May 4, 2015, to January 13, 2017.

Main outcomes and measures

Influence of HPV testing on disease yield, time to histologicall

SUBMITTER: Cuzick J 

PROVIDER: S-EPMC5710525 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature