Optic Nerve Infiltration in Primary Central Nervous System Lymphoma.

ABSTRACT:

Importance

Visual impairment in primary central nervous system lymphoma (PCNSL) is caused mostly by intraocular lymphomatous involvement (vitritis and retinal infiltration), whereas optic nerve infiltration (ONI) is a rare condition.

Objective

To describe the clinical presentation of ONI, its imaging characteristics, and outcome.

Design, setting and participants

A total of 752 patients diagnosed with PCNSL were retrospectively identified from the databases of 3 French hospitals from January 1, 1998, through December 31, 2014. Of these, 7 patients had documented ONI. Exclusion criteria were intraocular involvement, orbital lymphoma, or other systemic lymphoma. Clinical presentation, neuroimaging, biological features, treatment, and outcomes were assessed.

Main outco

SUBMITTER: Ahle G 

PROVIDER: S-EPMC5710580 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature