Association of Childhood Body Mass Index and Change in Body Mass Index With First Adult Ischemic Stroke.

ABSTRACT:

Importance

The incidence of ischemic stroke among young adults is rising and is potentially due to an increase in stroke risk factors occurring at younger ages, such as obesity.

Objectives

To investigate whether childhood body mass index (BMI) and change in BMI are associated with adult ischemic stroke and to assess whether the associations are age dependent or influenced by birth weight.

Design, setting, and participants

This investigation was a population-based cohort study of schoolchildren born from 1930 to 1987, with follow-up through national health registers from 1977 to 2012 in Denmark. Participants were 307 677 individuals (8899 ischemic stroke cases) with measured weight and height at ages 7 to 13 years. The dates of the analysis were September 1, 2015, to M

SUBMITTER: Gjærde LK 

PROVIDER: S-EPMC5710582 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature