Long-term Safety and Efficacy of New-Generation Drug-Eluting Stents in Women With Acute Myocardial Infarction: From the Women in Innovation and Drug-Eluting Stents (WIN-DES) Collaboration.

ABSTRACT:

Importance

Women with acute myocardial infarction (MI) undergoing mechanical reperfusion remain at increased risk of adverse cardiac events and mortality compared with their male counterparts. Whether the benefits of new-generation drug-eluting stents (DES) are preserved in women with acute MI remains unclear.

Objective

To investigate the long-term safety and efficacy of new-generation DES vs early-generation DES in women with acute MI.

Design, setting, and participants

Collaborative, international, individual patient-level data of women enrolled in 26 randomized clinical trials of DES were analyzed between July and December 2016. Only women presenting with an acute coronary syndrome were included. Study population was categorized according to presentation with unstab

SUBMITTER: Giustino G 

PROVIDER: S-EPMC5710588 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature