Association of Neonatal Glycemia With Neurodevelopmental Outcomes at 4.5 Years.

ABSTRACT:

Importance

Hypoglycemia is common during neonatal transition and may cause permanent neurological impairment, but optimal intervention thresholds are unknown.

Objective

To test the hypothesis that neurodevelopment at 4.5 years is related to the severity and frequency of neonatal hypoglycemia.

Design, setting, and participants

The Children With Hypoglycemia and Their Later Development (CHYLD) Study is a prospective cohort investigation of moderate to late preterm and term infants born at risk of hypoglycemia. Clinicians were masked to neonatal interstitial glucose concentrations; outcome assessors were masked to neonatal glycemic status. The setting was a regional perinatal center in Hamilton, New Zealand. The study was conducted from December 2006 to November 2010. Th

SUBMITTER: McKinlay CJD 

PROVIDER: S-EPMC5710616 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature