Association of Transcatheter Aortic Valve Replacement With 30-Day Renal Function and 1-Year Outcomes Among Patients Presenting With Compromised Baseline Renal Function: Experience From the PARTNER 1 Trial and Registry.

ABSTRACT:

Importance

The frequency of baseline renal impairment among high-risk and inoperable patients with severe aortic stenosis undergoing a transcatheter aortic valve replacement (TAVR) and the effect of TAVR on subsequent renal function are, to our knowledge, unknown.

Objective

To determine the effect of TAVR among patients with baseline renal impairment.

Design, setting, and participants

This substudy of patients with baseline renal impairment (estimated glomerular filtration rate [eGFR] ≤ 60 mL/min) and paired baseline and 30-day measures of renal function undergoing TAVR in the PARTNER 1 trial and continued access registries was conducted in 25 centers in the United States and Canada.

Main outcomes and measures

Patients were categorized with improved eGFR (30-da

SUBMITTER: Beohar N 

PROVIDER: S-EPMC5710618 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature