Assessment of a Person-Level Risk Calculator to Predict New-Onset Bipolar Spectrum Disorder in Youth at Familial Risk.

ABSTRACT:

Importance

Early identification of individuals at high risk for the onset of bipolar spectrum disorder (BPSD) is key from both a clinical and research perspective. While previous work has identified the presence of a bipolar prodrome, the predictive implications for the individual have not been assessed, to date.

Objective

To build a risk calculator to predict the 5-year onset of BPSD in youth at familial risk for BPSD.

Design, setting, and participants

The Pittsburgh Bipolar Offspring Study is an ongoing community-based longitudinal cohort investigation of offspring of parents with bipolar I or II (and community controls), recruited between November 2001 and July 2007, with a median follow-up period of more than 9 years. Recruitment has ended, but follow-up is ongoin

SUBMITTER: Hafeman DM 

PROVIDER: S-EPMC5710639 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature